From July 1 more than 1300 traffic lights will be adjusted to automatically turn green so that chauffeur-driven dignitaries can be hurried around the Olympic Route Network in the VIP lanes.
In the same period, ordinary Londoners are being asked to work from home or travel early or late to work in order to avoid chaos on the trains and tubes.
Transport for London (TfL) also said that traffic will start to build up significantly two weeks before the Games, when athletes, world media and dignitaries begin to arrive.
TfL commissioner Peter Hendy said: “From mid-July, central London and areas around Games venues will be much busier than usual. The ORN, which is part of the host city contract for the Games, will be a vital part of managing the busy roads and delivering a great Games.
“It will come into operation on July 25, a couple of days before the opening ceremony.
“Our advice to motorists is clear. From mid-July, avoid driving in central London, around the ORN and Games venues.”
The designated lanes are set aside for athletes, coaches, administrators and 25,000 ‘marketing partners’.