Scotland have not advanced beyond the quarter-finals at the Rugby World Cup since 1991.
Two tries for Australia would see them record their 200th in the RWC.
This will be the second RWC meeting between these sides having met at the same stage in 2003, when Australia won 33-16.
Australia have won 17 of their last 19 Test matches against Scotland.
Scotland have won just four times in 47 Tests at Twickenham with the last of these triumphs coming in 1983.
David Pocock won more turnovers (10) than any other player in the pool stages, in spite of playing in just three matches (219 minutes).
Scotland made more tackles (592) than any other side in the pool stages, and still upheld the third best success rate (90%).
Scotland accepted fewer turnovers (43) than any other team in the pool stages.
