Nicklinson, 58, was left paralysed from the neck down after suffering a stroke seven years ago.
He went to court to seek assurance that anyone who helped him end his life would avoid prosecution. But when last week’s ruling refused his plea, Nicklinson issued a statement to convey his disappointment.
“I am saddened that the law wants to condemn me to a life of increasing indignity and misery,” Nicklinson said, via his lawyers.
He had reportedly been planning to appeal.
His death was announced via Twitter, with Nicklinson’s daughters posting a message from his account.
It read: “You may already know, my Dad died peacefully this morning of natural causes. He was 58. Before he died, he asked us to tweet: ‘Goodbye world, the time has come, I had some fun.’ Thank you for your support over the years. We would appreciate some privacy at this difficult time. Love, Jane, Lauren and Beth.”
Last week’s denial in court of Nicklinson’s right to die was based on the argument that it was for parliament and not the courts to change the law.